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The Importance of Mitochondrial Pyruvate Carrier in Cancer Cell Metabolism and Tumorigenesis

SIMPLE SUMMARY: The characteristic metabolic hallmark of cancer cells is the massive catabolism of glucose by glycolysis, even under aerobic conditions—the so-called Warburg effect. Although energetically unfavorable, glycolysis provides “building blocks” to sustain the unlimited growth of malignant...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ruiz-Iglesias, Ainhoa, Mañes, Santos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037430/
https://ncbi.nlm.nih.gov/pubmed/33804985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071488
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