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Mitochondrial Pyruvate Carrier Function and Cancer Metabolism

Metabolic reprograming in cancer supports the increased biosynthesis required for unchecked proliferation. Increased glucose utilization is a defining feature of many cancers that is accompanied by altered pyruvate partitioning and mitochondrial metabolism. Cancer cells also require mitochondrial tr...

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Bibliografske podrobnosti
izdano v:Curr Opin Genet Dev
Main Authors: Rauckhorst, Adam J., Taylor, Eric B.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017534/
https://ncbi.nlm.nih.gov/pubmed/27269731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2016.05.003
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