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Breast Cancer Patient Prognosis Is Determined by the Interplay between TP53 Mutation and Alternative Transcript Expression: Insights from TP53 Long Amplicon Digital PCR Assays

SIMPLE SUMMARY: The TP53 gene, the most commonly mutated gene in human cancers, is capable of producing multiple RNAs (transcripts). The aim of our study was to measure the abundance of each TP53 transcript, combined with TP53 gene mutation information, to determine the interplay between these in a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Lasham, Annette, Knowlton, Nicholas, Mehta, Sunali Y., Braithwaite, Antony W., Print, Cristin G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036703/
https://ncbi.nlm.nih.gov/pubmed/33810361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071531
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