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Breast Cancer Patient Prognosis Is Determined by the Interplay between TP53 Mutation and Alternative Transcript Expression: Insights from TP53 Long Amplicon Digital PCR Assays

SIMPLE SUMMARY: The TP53 gene, the most commonly mutated gene in human cancers, is capable of producing multiple RNAs (transcripts). The aim of our study was to measure the abundance of each TP53 transcript, combined with TP53 gene mutation information, to determine the interplay between these in a...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Lasham, Annette, Knowlton, Nicholas, Mehta, Sunali Y., Braithwaite, Antony W., Print, Cristin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036703/
https://ncbi.nlm.nih.gov/pubmed/33810361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071531
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