Cardiac Oxidative Signaling and Physiological Hypertrophy in the Na/K-ATPase α1(s/s)α2(s/s) Mouse Model of High Affinity for Cardiotonic Steroids

The Na/K-ATPase is the specific receptor for cardiotonic steroids (CTS) such as ouabain and digoxin. At pharmacological concentrations used in the treatment of cardiac conditions, CTS inhibit the ion-pumping function of Na/K-ATPase. At much lower concentrations, in the range of those reported for en...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Marck, Pauline V., Pessoa, Marco T., Xu, Yunhui, Kutz, Laura C., Collins, Dominic M., Yan, Yanling, King, Cierra, Wang, Xiaoliang, Duan, Qiming, Cai, Liquan, Xie, Jeffrey X., Lingrel, Jerry B., Xie, Zijian, Tian, Jiang, Pierre, Sandrine V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036649/
https://ncbi.nlm.nih.gov/pubmed/33801629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073462
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