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Impact of Different JAK Inhibitors and Methotrexate on Lymphocyte Proliferation and DNA Damage

Janus kinase inhibitors (JAKis) represent a new strategy in rheumatoid arthritis (RA) therapy. Still, data directly comparing different JAKis are rare. In the present in vitro study, we investigated the immunomodulatory potential of four JAKis (tofacitinib, baricitinib, upadacitinib, and filgotinib)...

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Bibliografske podrobnosti
izdano v:J Clin Med
Main Authors: Reddig, Annika, Voss, Linda, Guttek, Karina, Roggenbuck, Dirk, Feist, Eugen, Reinhold, Dirk
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036268/
https://ncbi.nlm.nih.gov/pubmed/33916057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10071431
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