Screening of FDA-Approved Drug Library Identifies Adefovir Dipivoxil as Highly Potent Inhibitor of T Cell Proliferation

Repositioning of approved drugs for identifying new therapeutic purposes is an alternative, time and cost saving strategy to classical drug development. Here, we screened a library of 786 FDA-approved drugs to find compounds, which can potentially be repurposed for treatment of T cell-mediated autoi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Voss, Linda, Guttek, Karina, Reddig, Annika, Reinhold, Annegret, Voss, Martin, Schraven, Burkhart, Reinhold, Dirk
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821167/
https://ncbi.nlm.nih.gov/pubmed/33488629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.616570
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