Immune Cell-Type Specific Ablation of Adapter Protein ADAP Differentially Modulates EAE

The cytosolic adhesion and degranulation-promoting adapter protein ADAP is expressed in various hematopoietic cells including T cells, NK cells, myeloid cells, and platelets but absent in mature B cells. The role of ADAP in T cell activation, proliferation and integrin activation is well-accepted. W...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rudolph, Jochen, Meinke, Clara, Voss, Martin, Guttek, Karina, Kliche, Stefanie, Reinhold, Dirk, Schraven, Burkhart, Reinhold, Annegret
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779796/
https://ncbi.nlm.nih.gov/pubmed/31632410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02343
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