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Methotrexate Is a JAK/STAT Pathway Inhibitor
BACKGROUND: The JAK/STAT pathway transduces signals from multiple cytokines and controls haematopoiesis, immunity and inflammation. In addition, pathological activation is seen in multiple malignancies including the myeloproliferative neoplasms (MPNs). Given this, drug development efforts have targe...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489434/ https://ncbi.nlm.nih.gov/pubmed/26131691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130078 |
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