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Methotrexate Is a JAK/STAT Pathway Inhibitor
BACKGROUND: The JAK/STAT pathway transduces signals from multiple cytokines and controls haematopoiesis, immunity and inflammation. In addition, pathological activation is seen in multiple malignancies including the myeloproliferative neoplasms (MPNs). Given this, drug development efforts have targe...
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| Gepubliceerd in: | PLoS One |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489434/ https://ncbi.nlm.nih.gov/pubmed/26131691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130078 |
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