Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway

BACKGROUND: Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as library design and post-screening bioinformatics may be effecting the data gene...

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Detalhes bibliográficos
Main Authors: Fisher, Katherine H, Wright, Victoria M, Taylor, Amy, Zeidler, Martin P, Brown, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526451/
https://ncbi.nlm.nih.gov/pubmed/23006893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-506
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