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Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway

BACKGROUND: Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as library design and post-screening bioinformatics may be effecting the data gene...

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מידע ביבליוגרפי
Main Authors: Fisher, Katherine H, Wright, Victoria M, Taylor, Amy, Zeidler, Martin P, Brown, Stephen
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526451/
https://ncbi.nlm.nih.gov/pubmed/23006893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-506
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