Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway

BACKGROUND: Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as library design and post-screening bioinformatics may be effecting the data gene...

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Bibliographic Details
Main Authors: Fisher, Katherine H, Wright, Victoria M, Taylor, Amy, Zeidler, Martin P, Brown, Stephen
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526451/
https://ncbi.nlm.nih.gov/pubmed/23006893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-506
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