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Role and therapeutic potential of liquid–liquid phase separation in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative disease selectively affecting motor neurons, leading to progressive paralysis. Although most cases are sporadic, ∼10% are familial. Similar proteins are found in aggregates in sporadic and familial ALS, and over the last decade, r...
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| Publicado no: | J Mol Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8036000/ https://ncbi.nlm.nih.gov/pubmed/32976566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjaa049 |
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