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Effect of Synchronous Versus Sequential Regimens on the Pharmacokinetics and Biodistribution of Regorafenib with Irradiation

This study was performed to evaluate the interaction between conventional or high-dose radiotherapy (RT) and the pharmacokinetics (PK) of regorafenib in concurrent or sequential regimens for the treatment of hepatocellular carcinoma. Concurrent and sequential in vitro and in vivo studies of irradiat...

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Опубликовано в: :Pharmaceutics
Главные авторы: Tsai, Tung-Hu, Chen, Yu-Jen, Wang, Li-Ying, Hsieh, Chen-Hsi
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035703/
https://ncbi.nlm.nih.gov/pubmed/33805831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030386
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