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Effect of Synchronous Versus Sequential Regimens on the Pharmacokinetics and Biodistribution of Regorafenib with Irradiation

This study was performed to evaluate the interaction between conventional or high-dose radiotherapy (RT) and the pharmacokinetics (PK) of regorafenib in concurrent or sequential regimens for the treatment of hepatocellular carcinoma. Concurrent and sequential in vitro and in vivo studies of irradiat...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Tsai, Tung-Hu, Chen, Yu-Jen, Wang, Li-Ying, Hsieh, Chen-Hsi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035703/
https://ncbi.nlm.nih.gov/pubmed/33805831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030386
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