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Mechanisms and therapeutic implications of cellular senescence in osteoarthritis
The development of osteoarthritis (OA) correlates with a rise in the number of senescent cells in joint tissues, and the senescence-associated secretory phenotype (SASP) has been implicated in cartilage degradation and OA. Age-related mitochondrial dysfunction and associated oxidative stress might i...
Shranjeno v:
| izdano v: | Nat Rev Rheumatol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8035495/ https://ncbi.nlm.nih.gov/pubmed/33208917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41584-020-00533-7 |
| Oznake: |
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