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Mechanisms and therapeutic implications of cellular senescence in osteoarthritis
The development of osteoarthritis (OA) correlates with a rise in the number of senescent cells in joint tissues, and the senescence-associated secretory phenotype (SASP) has been implicated in cartilage degradation and OA. Age-related mitochondrial dysfunction and associated oxidative stress might i...
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| 出版年: | Nat Rev Rheumatol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8035495/ https://ncbi.nlm.nih.gov/pubmed/33208917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41584-020-00533-7 |
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