Chargement en cours...

Deletion of c-Jun N-terminal Kinase Enhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice

OBJECTIVE. Determine the role of c-Jun N-terminal kinase (JNK) signaling in the development of osteoarthritis (OA) induced by joint injury and aging in mice. METHODS. Destabilization of the medial meniscus (DMM) or sham surgery was performed on 12 week-old mice and OA evaluated 8 weeks after surgery...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Arthritis Rheumatol
Auteurs principaux: Loeser, Richard F., Kelley, Kathryn L., Armstrong, Alexandra, Collins, John A., Diekman, Brian O., Carlson, Cathy S.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669715/
https://ncbi.nlm.nih.gov/pubmed/32418287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41312
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!