SLPI is a critical mediator that controls PTH-induced bone formation

Osteoclastic bone resorption and osteoblastic bone formation/replenishment are closely coupled in bone metabolism. Anabolic parathyroid hormone (PTH), which is commonly used for treating osteoporosis, shifts the balance from osteoclastic to osteoblastic, although it is unclear how these cells are co...

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Publié dans:Nat Commun
Auteurs principaux: Morimoto, Akito, Kikuta, Junichi, Nishikawa, Keizo, Sudo, Takao, Uenaka, Maki, Furuya, Masayuki, Hasegawa, Tetsuo, Hashimoto, Kunihiko, Tsukazaki, Hiroyuki, Seno, Shigeto, Nakamura, Akira, Okuzaki, Daisuke, Sugihara, Fuminori, Ninomiya, Akinori, Yoshimura, Takeshi, Takao-Kawabata, Ryoko, Matsuda, Hideo, Ishii, Masaru
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035405/
https://ncbi.nlm.nih.gov/pubmed/33837198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22402-x
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