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Development of an intravital imaging system for the synovial tissue reveals the dynamics of CTLA-4 Ig in vivo

There have been many attempts to visualize the inflamed joints using multiphoton microscopy. However, due to the hypervascular and multilayered structure of the inflamed synovium, intravital imaging of the deep synovial tissue has been difficult. Here, we established original intravital imaging syst...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Hasegawa, Tetsuo, Kikuta, Junichi, Sudo, Takao, Yamashita, Erika, Seno, Shigeto, Takeuchi, Tsutomu, Ishii, Masaru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417741/
https://ncbi.nlm.nih.gov/pubmed/32778803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70488-y
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