SLPI is a critical mediator that controls PTH-induced bone formation

Osteoclastic bone resorption and osteoblastic bone formation/replenishment are closely coupled in bone metabolism. Anabolic parathyroid hormone (PTH), which is commonly used for treating osteoporosis, shifts the balance from osteoclastic to osteoblastic, although it is unclear how these cells are co...

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Vydáno v:Nat Commun
Hlavní autoři: Morimoto, Akito, Kikuta, Junichi, Nishikawa, Keizo, Sudo, Takao, Uenaka, Maki, Furuya, Masayuki, Hasegawa, Tetsuo, Hashimoto, Kunihiko, Tsukazaki, Hiroyuki, Seno, Shigeto, Nakamura, Akira, Okuzaki, Daisuke, Sugihara, Fuminori, Ninomiya, Akinori, Yoshimura, Takeshi, Takao-Kawabata, Ryoko, Matsuda, Hideo, Ishii, Masaru
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035405/
https://ncbi.nlm.nih.gov/pubmed/33837198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22402-x
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