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Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay

Clostridium botulinum neurotoxin serotype A (BoNT/A) is a potent neurotoxin that serves as an effective therapeutic for several neuromuscular disorders via induction of temporary muscular paralysis. Specific binding and internalization of BoNT/A into neuronal cells is mediated by its binding domain...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: James, Nicholas G., Malik, Shiazah, Sanstrum, Bethany J., Rhéaume, Catherine, Broide, Ron S., Jameson, David M., Brideau-Andersen, Amy, Jacky, Birgitte S.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035261/
https://ncbi.nlm.nih.gov/pubmed/33837264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87331-7
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