Identification of Fibroblast Growth Factor Receptor 3 (FGFR3) as a Protein Receptor for Botulinum Neurotoxin Serotype A (BoNT/A)

Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25(206)) to yield SNAP25(197). Cleavage of SNAP25 results in blockage of synaptic vesicle fusion and inhibiti...

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Detalhes bibliográficos
Main Authors: Jacky, Birgitte P. S., Garay, Patton E., Dupuy, Jérôme, Nelson, Jeremy B., Cai, Brian, Molina, Yanira, Wang, Joanne, Steward, Lance E., Broide, Ron S., Francis, Joseph, Aoki, K. Roger, Stevens, Raymond C., Fernández-Salas, Ester
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656097/
https://ncbi.nlm.nih.gov/pubmed/23696738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003369
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