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A novel SHAPE reagent enables the analysis of RNA structure in living cells with unprecedented accuracy

Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being able to accurately define the folding of RNA molecules within living cells has become a crucial need. We introduce here 2-aminopyridine-3-carboxylic aci...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Marinus, Tycho, Fessler, Adam B, Ogle, Craig A, Incarnato, Danny
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034653/
https://ncbi.nlm.nih.gov/pubmed/33398343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1255
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