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RNA SHAPE analysis in living cells
RNA structure plays important roles in practically every facet of gene regulation, but the paucity of structural probes that function in vivo has limited current understanding. Here we design, synthesize, and demonstrate two novel chemical probes that enable selective 2’-hydroxyl acylation for accur...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706714/ https://ncbi.nlm.nih.gov/pubmed/23178934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1131 |
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