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Interrogating accessibility of telomeric sequences with FRET-PAINT: evidence for length-dependent telomere compaction

Single-stranded telomeric overhangs are ∼200 nucleotides long and can form tandem G-quadruplex (GQ) structures, which reduce their accessibility to nucleases and proteins that activate DNA damage response. Whether these tandem GQs further stack to form compact superstructures, which may provide bett...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Mustafa, Golam, Shiekh, Sajad, GC, Keshav, Abeysirigunawardena, Sanjaya, Balci, Hamza
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034622/
https://ncbi.nlm.nih.gov/pubmed/33693934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab067
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