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Interrogating accessibility of telomeric sequences with FRET-PAINT: evidence for length-dependent telomere compaction

Single-stranded telomeric overhangs are ∼200 nucleotides long and can form tandem G-quadruplex (GQ) structures, which reduce their accessibility to nucleases and proteins that activate DNA damage response. Whether these tandem GQs further stack to form compact superstructures, which may provide bett...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Mustafa, Golam, Shiekh, Sajad, GC, Keshav, Abeysirigunawardena, Sanjaya, Balci, Hamza
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034622/
https://ncbi.nlm.nih.gov/pubmed/33693934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab067
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