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Impact of Small Molecules on Intermolecular G-Quadruplex Formation

We performed single molecule studies to investigate the impact of several prominent small molecules (the oxazole telomestatin derivative L2H2-6OTD, pyridostatin, and Phen-DC(3)) on intermolecular G-quadruplex (i-GQ) formation between two guanine-rich DNA strands that had 3-GGG repeats in one strand...

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Publicat a:Molecules
Autors principals: Gyawali, Prabesh, GC, Keshav, Ma, Yue, Abeysirigunawardena, Sanjaya, Nagasawa, Kazuo, Balci, Hamza
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514588/
https://ncbi.nlm.nih.gov/pubmed/31010019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24081570
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