Targeting DNA G-Quadruplexes with Helical Small Molecules

We previously identified quinoline-based oligoamide helical foldamers and a trimeric macrocycle as selective ligands of DNA quadruplexes. Their helical structures might permit targeting of the backbone loops and grooves of G-quadruplexes instead of the G-tetrads. Given the vast array of morphologies...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Müller, Sebastian, Laxmi-Reddy, Katta, Jena, Prakrit V, Baptiste, Benoit, Dong, Zeyuan, Godde, Frédéric, Ha, Taekjip, Rodriguez, Raphaël, Balasubramanian, Shankar, Huc, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284101/
https://ncbi.nlm.nih.gov/pubmed/25256604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402439
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