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Network-guided search for genetic heterogeneity between gene pairs

MOTIVATION: Correlating genetic loci with a disease phenotype is a common approach to improve our understanding of the genetics underlying complex diseases. Standard analyses mostly ignore two aspects, namely genetic heterogeneity and interactions between loci. Genetic heterogeneity, the phenomenon...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Gumpinger, Anja C, Rieck, Bastian, Grimm, Dominik G, Borgwardt, Karsten
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034561/
https://ncbi.nlm.nih.gov/pubmed/32573681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa581
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