mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications

BACKGROUND: The application of computational and multi-omics approaches has aided our understanding of carcinogenesis and the development of therapeutic strategies. NSC765598 is a novel small molecule derivative of salicylanilide. This study aims to investigate the ligand-protein interactions of NSC...

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Vydáno v:Front Oncol
Hlavní autoři: Lawal, Bashir, Lee, Ching-Yu, Mokgautsi, Ntlotlang, Sumitra, Maryam Rachmawati, Khedkar, Harshita, Wu, Alexander T.H., Huang, Hsu-Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034425/
https://ncbi.nlm.nih.gov/pubmed/33842373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.656738
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