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Thermoneutrality Alters Gastrointestinal Antigen Passage Patterning and Predisposes to Oral Antigen Sensitization in Mice

Food allergy is an emerging epidemic, and the underlying mechanisms are not well defined partly due to the lack of robust adjuvant free experimental models of dietary antigen sensitization. As housing mice at thermoneutrality (Tn) - the temperature of metabolic homeostasis (26–30°C) – has been shown...

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Pubblicato in:Front Immunol
Autori principali: Noah, Taeko K., Lee, Jee-Boong, Brown, Christopher A., Yamani, Amnah, Tomar, Sunil, Ganesan, Varsha, Newberry, Rodney D., Huffnagle, Gary B., Divanovic, Senad, Hogan, Simon P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034294/
https://ncbi.nlm.nih.gov/pubmed/33841417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.636198
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