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Thermoneutrality Alters Gastrointestinal Antigen Passage Patterning and Predisposes to Oral Antigen Sensitization in Mice

Food allergy is an emerging epidemic, and the underlying mechanisms are not well defined partly due to the lack of robust adjuvant free experimental models of dietary antigen sensitization. As housing mice at thermoneutrality (Tn) - the temperature of metabolic homeostasis (26–30°C) – has been shown...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Noah, Taeko K., Lee, Jee-Boong, Brown, Christopher A., Yamani, Amnah, Tomar, Sunil, Ganesan, Varsha, Newberry, Rodney D., Huffnagle, Gary B., Divanovic, Senad, Hogan, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034294/
https://ncbi.nlm.nih.gov/pubmed/33841417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.636198
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