Thermoneutrality Alters Gastrointestinal Antigen Passage Patterning and Predisposes to Oral Antigen Sensitization in Mice

Food allergy is an emerging epidemic, and the underlying mechanisms are not well defined partly due to the lack of robust adjuvant free experimental models of dietary antigen sensitization. As housing mice at thermoneutrality (Tn) - the temperature of metabolic homeostasis (26–30°C) – has been shown...

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Udgivet i:Front Immunol
Main Authors: Noah, Taeko K., Lee, Jee-Boong, Brown, Christopher A., Yamani, Amnah, Tomar, Sunil, Ganesan, Varsha, Newberry, Rodney D., Huffnagle, Gary B., Divanovic, Senad, Hogan, Simon P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034294/
https://ncbi.nlm.nih.gov/pubmed/33841417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.636198
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