Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening

[Image: see text] Inositol hexakisphosphate kinases (IP6Ks) catalyze pyrophosphorylation of inositol hexakisphosphate (IP6) into inositol 5-diphospho-1,2,3,4,6-pentakisphosphate (IP7), which is involved in numerous areas of cell physiology including glucose homeostasis, blood coagulation, and neurol...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:ACS Pharmacol Transl Sci
Main Authors: Liao, Gangling, Ye, Wenjuan, Heitmann, Tyler, Ernst, Glen, DePasquale, Michael, Xu, Laiyi, Wormald, Michael, Hu, Xin, Ferrer, Marc, Harmel, Robert K., Fiedler, Dorothea, Barrow, James, Wei, Huijun
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2021
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033760/
https://ncbi.nlm.nih.gov/pubmed/33860201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00218
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares