An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis

BACKGROUND: Ichthyoses are rare, debilitating disorders associated with generalized scaling, erythema, and epidermal barrier impairment. Pathogenesis-based therapy is largely lacking, since the underlying molecular basis is poorly understood. OBJECTIVE: To characterize molecularly cutaneous inflamma...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Paller, Amy S., Renert-Yuval, Yael, Oliva, Margeaux, Esaki, Hitokazu, Suprun, Maria, Huynh, Thy Nhat, Ungar, Benjamin, Friedland, Rivka, Peng, Xiangyu, Zheng, Xiuzhong, Estrada, Yeriel D., Krueger, James G., Choate, Keith A., Suárez-Fariñas, Mayte, Guttman-Yassky, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033419/
https://ncbi.nlm.nih.gov/pubmed/27554821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.07.019
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