Early pediatric atopic dermatitis shows only a CLA(+) Th2/Th1 imbalance, while adults acquire CLA(+) Th22/Tc22 subsets

BACKGROUND: Identifying differences and similarities between CLA(+) polarized T-cell subsets in pediatric vs. adult atopic dermatitis (AD) is critical for directing new treatments towards children. OBJECTIVE: To compare activation markers and frequencies of skin-homing (CLA(+)) vs. systemic (CLA(−))...

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Publicat a:J Allergy Clin Immunol
Autors principals: Czarnowicki, Tali, Esaki, Hitokazu, Gonzalez, Juana, Malajian, Dana, Shemer, Avner, Noda, Shinji, Talasila, Sreya, Berry, Adam, Gray, Jayla, Becker, Lauren, Estrada, Yeriel, Xu, Hui, Zheng, Xiuzhong, Krueger, James G, Paller, Amy S, Guttman-Yassky, Emma
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946641/
https://ncbi.nlm.nih.gov/pubmed/26242300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.05.049
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