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Progressive activation of Th2/Th22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

BACKGROUND: Atopic dermatitis (AD) is a common disease, with an increasing prevalence. The primary pathogenesis of the disease is still elusive, resulting in the lack of specific treatments. AD is currently considered a biphasic disease, with Th2 predominating acute disease, and a switch to Th1 char...

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Autori principali: Gittler, Julia K., Shemer, Avner, Suárez-Fariñas, Mayte, Fuentes-Duculan, Judilyn, Gulewicz, Kara J., Wang, Claire Q.F., Mitsui, Hiroshi, Cardinale, Irma, de Guzman Strong, Cristina, Krueger, James G., Guttman-Yassky, Emma
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991245/
https://ncbi.nlm.nih.gov/pubmed/22951056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.07.012
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