Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1

BACKGROUND: Interleukin-28A (IL-28A or interferon-λ2) is reported to maintain intestinal mucosal homeostasis. However, the effects and mechanisms of IL-28A on intestinal ischemia reperfusion (I/R) have not yet been studied. METHODS: Adult C57BL/6 mice were randomly divided into three groups: sham, I...

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Bibliographic Details
Published in:Ann Transl Med
Main Authors: Li, Liangzi, Zhou, Chao, Li, Teming, Xiao, Weidong, Yu, Min, Yang, Hua
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2021
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033364/
https://ncbi.nlm.nih.gov/pubmed/33842586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5494
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