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Rack1 maintains intestinal homeostasis by protecting the integrity of the epithelial barrier

Previously, we generated mouse models of Rack1 deficiency to identify key functions for Rack1 in regulating growth of intestinal epithelia: suppressing crypt cell proliferation and regeneration, promoting differentiation and apoptosis, and repressing development of neoplasia. However, other than low...

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Detalles Bibliográficos
Publicado en:Am J Physiol Gastrointest Liver Physiol
Main Authors: Cheng, Zhuan-Fen, Cartwright, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866421/
https://ncbi.nlm.nih.gov/pubmed/29025732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00241.2017
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