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Rack1 function in intestinal epithelia: regulating crypt cell proliferation and regeneration and promoting differentiation and apoptosis

Previously, we showed that receptor for activated C kinase 1 (Rack1) regulates growth of colon cells in vitro, partly by suppressing Src kinase activity at key cell cycle checkpoints, in apoptotic and cell survival pathways and at cell-cell adhesions. Here, we generated mouse models of Rack1 deficie...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Gastrointest Liver Physiol
Asıl Yazarlar: Cheng, Zhuan-Fen, Pai, Reetesh K., Cartwright, Christine A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866376/
https://ncbi.nlm.nih.gov/pubmed/28935684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00240.2017
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