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Rack1 maintains intestinal homeostasis by protecting the integrity of the epithelial barrier

Previously, we generated mouse models of Rack1 deficiency to identify key functions for Rack1 in regulating growth of intestinal epithelia: suppressing crypt cell proliferation and regeneration, promoting differentiation and apoptosis, and repressing development of neoplasia. However, other than low...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Gastrointest Liver Physiol
Main Authors: Cheng, Zhuan-Fen, Cartwright, Christine A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866421/
https://ncbi.nlm.nih.gov/pubmed/29025732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00241.2017
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