Intestinal Epithelial Cells-Derived Hypoxia-Inducible Factor-1α Is Essential for the Homeostasis of Intestinal Intraepithelial Lymphocytes

Hif-1α is a master regulator which involved in the transcriptional regulation of anti-inflammatory or cellular responding to hypoxia. Previous work shows that the absence of Hif-1α results in the destruction of intestinal epithelial cell (IEC) and abnormalities of intestinal barrier function. Howeve...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sun, Lihua, Li, Teming, Tang, Hanlin, Yu, Kun, Ma, Yuanhang, Yu, Min, Qiu, Yuan, Xu, Pengyuan, Xiao, Weidong, Yang, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476974/
https://ncbi.nlm.nih.gov/pubmed/31040849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00806
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