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Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes

NOD2 functions as an intracellular sensor for microbial pathogen and plays an important role in epithelial defense. The loss-of-function mutation of NOD2 is strongly associated with human Crohn’s disease (CD). However, the mechanisms of how NOD2 maintains the intestinal homeostasis and regulates the...

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Bibliografske podrobnosti
Main Authors: Jiang, Wei, Wang, Xiaqiong, Zeng, Benhua, Liu, Lei, Tardivel, Aubry, Wei, Hong, Han, Jiahuai, MacDonald, H. Robson, Tschopp, Jurg, Tian, Zhigang, Zhou, Rongbin
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804938/
https://ncbi.nlm.nih.gov/pubmed/24062413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122490
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