Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis

Inflammasomes are involved in gut homeostasis and inflammatory pathologies, but the role of NLRP3 inflammasome in these processes is not well understood. Cryopyrin-associated periodic syndrome (CAPS) patients with NLRP3 mutations have autoinflammation in skin, joints, and eyes, but not in the intest...

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Publicado no:Nat Commun
Main Authors: Yao, Xiaomin, Zhang, Chenhong, Xing, Yue, Xue, Guang, Zhang, Qianpeng, Pan, Fengwei, Wu, Guojun, Hu, Yingxin, Guo, Qiuhong, Lu, Ailing, Zhang, Xiaoming, Zhou, Rongbin, Tian, Zhigang, Zeng, Benhua, Wei, Hong, Strober, Warren, Zhao, Liping, Meng, Guangxun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711854/
https://ncbi.nlm.nih.gov/pubmed/29196621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01917-2
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