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The Interaction Mechanism of Intrinsically Disordered PP2A Inhibitor Proteins ARPP-16 and ARPP-19 With PP2A

Protein phosphatase 2A (PP2A) activity is critical for maintaining normal physiological cellular functions. PP2A is inhibited by endogenous inhibitor proteins in several pathological conditions including cancer. A PP2A inhibitor protein, ARPP-19, has recently been connected to several human cancer t...

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Bibliographische Detailangaben
Veröffentlicht in:Front Mol Biosci
Hauptverfasser: Thapa, Chandan, Roivas, Pekka, Haataja, Tatu, Permi, Perttu, Pentikäinen, Ulla
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032985/
https://ncbi.nlm.nih.gov/pubmed/33842550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.650881
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