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Autocrine IGF2 programmes β-cell plasticity under conditions of increased metabolic demand
When exposed to nutrient excess and insulin resistance, pancreatic β-cells undergo adaptive changes in order to maintain glucose homeostasis. The role that growth control genes, highly expressed in early pancreas development, might exert in programming β-cell plasticity in later life is a poorly stu...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8032793/ https://ncbi.nlm.nih.gov/pubmed/33833312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87292-x |
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