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Dimeric mimetic of BDNF loop 4 promotes survival of serum-deprived cell through TrkB-dependent apoptosis suppression

Brain-derived neurotrophic factor (BDNF) is involved in the regulation of neuronal cell growth, differentiation, neuroprotection and synaptic plasticity. Although aberrant BDNF/TrkB signaling is implicated in several neurological, neurodegenerative and psychiatric disorders, neurotrophin-based thera...

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Publicat a:Sci Rep
Autors principals: Zainullina, L. F., Vakhitova, Yu. V., Lusta, A. Yu., Gudasheva, T. A., Seredenin, S. B.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032782/
https://ncbi.nlm.nih.gov/pubmed/33833366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87435-0
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