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More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells

The liver is constantly exposed to mixtures of hepatotoxic compounds, such as food contaminants and pesticides. Dose addition is regularly assumed for mixtures in risk assessment, which however might not be sufficiently protective in case of synergistic effects. Especially the prediction of combinat...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Lasch, Alexandra, Marx-Stoelting, Philip, Braeuning, Albert, Lichtenstein, Dajana
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032629/
https://ncbi.nlm.nih.gov/pubmed/33575850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-02997-2
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