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Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies
PURPOSE: An influential covariate for pharmacokinetics is (body) size. Recently, the method of estimation of normal fat mass (NFM) has been advocated. Here, the relative contribution of fat mass, estimated as a fraction fat (Ffat), is used to explain differences in pharmacokinetic parameters. This c...
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| Publicado no: | Eur J Clin Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8032617/ https://ncbi.nlm.nih.gov/pubmed/33205282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-020-03042-4 |
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