Pharmacokinetics and pharmacodynamics of ticagrelor in subjects on hemodialysis and subjects with normal renal function

PURPOSE: This single-dose, randomized, open-label, parallel-group, and crossover study assessed pharmacokinetics (PK), pharmacodynamics (PD), and safety of ticagrelor in subjects on hemodialysis versus healthy subjects. METHODS: Hemodialysis subjects were randomized, receiving a single ticagrelor 90...

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Enregistré dans:
Détails bibliographiques
Publié dans:Eur J Clin Pharmacol
Auteurs principaux: Teng, Renli, Muldowney, Sharen, Zhao, Yonggang, Berg, Jolene Kay, Lu, Jonathan, Khan, Naeem D.
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2018
Sujets:
Pharmacokinetics and Disposition
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096709/
https://ncbi.nlm.nih.gov/pubmed/29850937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-018-2484-7
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